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The changes in systolic and diastolic BP and heart rate, between the run-in period and weeks 1 to 12 of snus cessation were tested using a paired 2-samples t test and presented as the means and 95% CI for each period, as well as the differences between them

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The area has to be smooth and hairless for the patch to stick in place and work as designed

They hypothesized that cotton wicks used in e-cigarette cartridges may be one source of contamination, as both endotoxin and glucan are known contaminants of cotton fibers